A Case for APRIL/BLyS Directed Therapy Not Eosinophil Directed Therapy for Alloantibody Elimination
نویسندگان
چکیده
منابع مشابه
Directed Therapy for Exfoliation Syndrome
Exfoliation syndrome (XFS) is an age-related disorder of the extracellular matrix that leads the production of abnormal fibrillar material that leads to elevated intraocular pressure and a relatively severe glaucoma. Exfoliation material is deposited in numerous ocular tissues and extraocular organs. XFS is associated with ocular ischemia, cerebrovascular disease, neurodegenerative disease and ...
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چکیده ندارد.
15 صفحه اولLiver Directed Therapy for Renal Cell Carcinoma
BACKGROUND Metastatic renal cell carcinoma (RCC) to the liver portrays a poor prognosis and liver directed therapy remains controversial. We aimed to determine potential selection criteria for patients who might benefit from this strategy. MATERIALS AND METHODS We evaluated 247 consecutive patients with RCC metastatic to the liver from a prospectively maintained database. RESULTS Eighteen p...
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Human epidermal growth factor receptor 2 (HER2) overexpression drives the biology of 20% of breast cancers, and predicts a poor prognosis for patients. HER2-targeted therapies significantly improve outcomes for HER2-positive patients with both early and metastatic breast cancer. Currently three HER2-targeted agents, trastuzumab (Herceptin), lapatinib (Tykerb), and pertuzumab (Perjeta), are avai...
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In an effort to develop more effective therapy for tuberculosis (TB), research efforts are looking toward host-directed therapy, reprograming the body's natural defenses to better control the infection. While significant progress is being made, the efforts are limited by lack of understanding of the pathology and pathogenesis of adult type TB disease. We have recently published evidence that th...
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ژورنال
عنوان ژورنال: American Journal of Transplantation
سال: 2013
ISSN: 1600-6135
DOI: 10.1111/ajt.12576